Everything about Cholesteatoma totally explained
Cholesteatoma is a destructive and expanding sac in the middle ear and/or
mastoid process.
Causes
There are two types: congenital and acquired. Acquired cholesteatomas can be caused by a tear or retraction of the
ear drum.
Usually cholesteatomas in adults are acquired through the above reasons. Less commonly the disease may be congenital, when it grows from birth behind the eardrum. Congenital cholesteatomas are more often found in the anterior aspect of the ear drum, in contrast to acquired cholesteatomas that usually arise from the pars flaccida region of the ear drum in the posterior-superior aspect of the ear drum.
Both the acquired as well as the congenital types of the disease can affect the
facial nerve that reaches from the brain to the face and leads through the inner and middle ear and leaves at the forward tip of the
mastoid bone, and then rises to the front of the ear and extends into the upper and lower face.
Presentation
The patient may have a recurrent ear discharge. Granulation tissue and a discharge (through a marginal perforation of the ear drum) may be seen on examination. A
cholesteatoma cyst consists of desquamating (peeling) layers of scaly or keratinised (horny) layers of
epithelium, which may also contain
cholesterol crystals. Often the debris is infected with
Pseudomonas aeruginosa.
If untreated, a cholesteatoma can eat into the three small bones located in the middle ear (the
malleus,
incus and
stapes, collectively called
ossicles), which can result in nerve deterioration,
deafness, imbalance and
vertigo. It can also affect and erode, through the
enzymes it produces, the thin bone structure that isolates the top of the ear from the brain, as well as lay the covering of the brain open to infection with serious complications.
A history of
ear infection or flooding of the ear during swimming should be taken seriously and investigated as cholesteatoma should be considered a possible outcome.
Symptoms
Common symptoms of cholesteatoma may include:
Hearing loss,
discharge from the ear (usually brown/yellow) with a strong odor, bleeding from the ear,
dizziness,
vertigo,
balance disruption,
ear ache,
headaches or
tinnitus. There can also be
facial nerve weakness.
Prognosis
Even after careful microscopic surgical removal, 10% to 20% of cholesteatomas may recur, which then require follow-up checks and/or treatment.
Tumor or not?
The status of cholesteatomas as
tumors is currently unresolved. There is some evidence to support the hypothesis that cholesteatomas are low-grade tumors however, recent studies have failed to show consistent DNA instability in cholesteatomas.
Further Information
Get more info on 'Cholesteatoma'.
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